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ajinar@ksau-hs.edu.sa 99,603

 Dr. Reham Ajina

Assistant Professor
Dr. Reham Ajina is an assistant professor in the department of Clinical Laboratory Sciences at King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), in Riyadh. Dr. Reham Ajina received a BS in Medical Laboratory Technology from King Abdulaziz University, and a MS in Biochemistry and Molecular Biology followed by a PhD in Tumor Biology, both from Georgetown University. She has several publications in peer-reviewed journals and received many research awards. Dr. Reham Ajina aspires to become a highly productive scientist with the capacity to make important contributions to the cancer immunology field. Mainly, she is interested in personalized cancer immunotherapy which involves studying the underlying mechanisms of immune resistance for each individual cancer patient.
Birth Date
Nationalty
Languages

EDUCATION & PROFESSIONAL EXPERIENCE

​​​​DEGREES:

Ph.D. in Tumor Biology, Georgetown University, USA

MSc in 

B.Sc. in 

​​​​​​PROFESSIONAL EXPERIENCE:

Feb.2021-Present: Assistant Professor, College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia 

July 2020-Feb.2021: Assistant Professor, College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia

Aug 2012-June 2020: Teaching Assistant, College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia​

HONORARY DEGREE &AWARDS

Feb. 2020Fall 2019 GradGov Research Project Award
Nov. 2019Georgetown University Medical Center Graduate Student Organization Travel Award
Aug. 2019SITC 2019 Young Investigator Award
July 2019Georgetown University Medical Center Graduate Student Organization Student Research Grant
June 2019The AACR Translational Cancer Research for Basic Scientists Workshop Award
May 2019Georgetown Breast Cancer Advocates (GBCA) Clarity in Science Award
​Apr. 2019The Dean for Medical Education's Academy for Research, Clinical, and Health Equity Scholarship (ARCHES) Research Fellowship program​
Apr. 2019Georgetown University Medical Center Graduate Student Organization Travel Award
Feb. 2019Georgetown University Medical Center Graduate Student Organization Course Award
Jan. 2019NIH-FAES Graduate School Student Scholarship Award
Apr. 2018Illumina NextSeq550-Genomics & Epigenomics Shared Resource (GESR), Georgetown University's Lombardi Comprehensive Cancer Center Award 
Mar. 2018Invited to reception with Saudi Crown Prince Mohammad Bin Salman in recognition of outstanding academic performance
Aug. 2014Full tuition scholarship to pursue my PhD degree, sponsored by King Saud bin Abdulaziz University for Health Sciences, Saudi Arabia
May 2014Graduated with honors and ranking 1st among Biochemistry and Molecular Biology majors at Georgetown University
Aug. 2013Full tuition scholarship to pursue my MS degree, sponsored by King Saud bin Abdulaziz University for Health Sciences, Saudi Arabia
Aug. 2012Graduated with honors and ranking 1st among Medical Laboratory Technology majors at King Abdulaziz University, Jeddah, Saudi Arabia
Aug. 2007Graduated from high school with one of the ten highest GPAs in Saudi Arabia



Research Interests / Collaborations

Publications

Google Scholars ​

R Ajina, ZX Malchiodi, AA Fitzgerald, A Zuo, S Wang, M Moussa, M Catalfamo, SJ Cooper, Y Shen, QR Johnson, JM Parks, JC Smith, EJ Fertig, SA Jablonski, LM Weiner. “Anti-Tumor T Cell Immunity Contributes to Pancreatic Cancer Immune Resistance" Cancer Immunology Research.

R Ajina, A Zuo, S Wang, M Moussa, M Catalfamo, SJ Cooper, Y Shen, QR Johnson, JM Parks, JC Smith, EJ Fertig, SA Jablonski, LM Weiner. “Immune Selection Pressure Contributes to Pancreatic Cancer Immune Evasion" bioRxiv.

R Ajina, LM Weiner. “T-Cell Immunity in Pancreatic Cancer" Pancreas. In Press. 

R Ajina, D J Zahavi, Y Zhang, and LM Weine. “Overcoming Malignant Cell Based Mechanisms of Resistance to Antibody-Targeted Cancer Immunotherapy" Seminars in Cancer Biology.

R Ajina, D Zamalin, A Zuo, M Moussa, M Catalfamo, SA Jablonski, LM Weiner. “SpCas9-expression by tumor cells can cause T cell-dependent tumor rejection in immunocompetent mice" OncoImmunology.

R Ajina, D Zamalin, LM Weiner. “Functional Genomics: Paving the Way for More Successful Cancer Immunotherapy." OUP Academic.

CW Shuptrine, R Ajina, EJ Fertig, SA Jablonski, HK Lyerly, ZC Hartman, LM Weiner.“An unbiased in vivo functional genomics screening approach in mice identifies novel tumor cell-based regulators of immune rejection",Cancer Immunology,Immunotherapy, 

R Ajina, D AlDeghaither, SA Jablonski, LM Weiner. "Cancer Immunotherapy." Comprehensive Medicinal Chemistry 3e.​


SCIENTIFIC MEMBERSHIPS AND ACTIVITIES

MEMBERSHIP OF SOCIETIES

The Saudi Society for Molecular Biology and Biotechnology (SSMBB society)

American Association for Cancer Research (AACR)

Women in Cancer Research (WICR)

Georgetown Women in Science and Education (GU WISE)

Society for Immunotherapy of Cancer (SITC)​

COMMUNITY CONTRIBUTIONS 

I participated in the Molecular Genetics and Precision Medicine Course and Workshop, and I gave a talk titled “Immunogenomics Applications Towards Precision Cancer Medicine". This course and workshop were organized by King Khalid Medical City Research Center (RC KKMC) that featured presentations by national and international experts with more than one hundred attendees (virtually, Sep. 12-13, 2021)

I am a working member in the Saudi Society for Molecular Biology and Biotechnology (SSMBB society) that involves Molecular Biology and Biotechnology experts from several Saudi clinical, academic and research institutes (Feb. 2022-Present)​

SCIENTIFIC PARTICIPATION

Peer-review committee member for the University of Tabuk​​

CONFERENCES/ WORKSHOP PARTICIPATIONS

2021
​R Ajina. Current Status of Regulatory Approved Immunotherapies in Saudi Arabia, 2021 AACR Virtual Special Conference: Tumor Immunology and Immunotherapy
2021 R Ajina. Immunogenomics Applications Towards Precision Cancer Medicine, Molecular Genetics and Genomic Course, King Fahad Specialist Hospital-Dammam
2020​ S Wang, A Fitzgerald, R Ajina, SA Jablonsk, LM. Weiner, J MacDougall, V Agarwal, VJ O'Neill. herapy with BXCL701 (B), a DPP8, DPP9, DPPIV and FAP inhibitor, in combination with anti-PD1 antibody (PD1) in a syngeneic murine pancreatic ductal adenocarcinoma (PDAC) model improves treatment outcomes and induces intratumoral NK cell infiltrates and a marked reduction in tumor stromal fibrosis [abstract]. Poster presentation delivered at AACR Annual Meeting 2020, April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA
2019

R Ajina, A Zuo, SA Jablonski, LM Weiner. Selective induction of S100a8/a9 heterodimer protein in pancreatic cancer in response to immune selection pressure [abstract]. Oral presentation delivered at the 34th SITC Annual Meeting, 2016 Nov 6-10; National Harbor (MD), 2019

2019 R Ajina, A Zuo, M Moussa, SJ Cooper, Y Shen, QR Johnson, JM Parks, JC Smith, E Fertig, M Catalfamo, SA Jablonski, LM Weiner. Malignant pancreatic cancer cells respond to immune selection pressure to foster immunosuppression [abstract].  Poster presentation delivered at AACR Annual Meeting 2019
2016 R Ajina, S Wang, J Smith, SA Jablonski, E Petricoin III, LM Weiner. Impact of immune selection pressure on epithelial cell signaling pathway activation in a syngeneic pancreatic cancer model [abstract]. Poster presentation delivered at the 31st SITC Annual Meeting, 2016 Nov 9-13; National Harbor (MD), 2016. Abstract nr. 385
2016 JP Smith, S Wang, R Ajina, SA Jablonski, and LM Weiner. Combination therapy with immune checkpoint inhibitor and CCK-receptor blockade increases survival of pancreatic cancer [abstract]. Poster presentation delivered at the AACR 107th Annual Meeting, 2016 Apr. 16-20; New Orleans (LA), 2016. Abstract nr. 4023​​

CONTACT INFORMATION


Contact information

Office location/number: College of Applied Medical Sciences-F 

Phone: +966 11 4299999    Ext 99603

Email: ajinar​@ksau-hs  ​​​